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CVD, ICU Stay Tied to Klebsiella Infection Post-Transplant

Among solid organ transplant recipients older than 50 years, over half had at least one infection episode of Klebsiella spp. within 180 days after transplantation. A history of cardiovascular disease and posttransplant ICU stay for three or more days were each significantly associated with a more than twofold increased risk.

Vasoplegia as a Distinct Hemodynamic Phenotype After Heart Transplantation

Vasoplegia is a known complication of cardiopulmonary bypass, but its prevalence and clinical significance after heart transplantation, especially when excluding primary graft dysfunction, are not well understood. This study aims to delineate post-transplant vasoplegia using a consensus framework, identify perioperative risk factors and assess its impact on post-transplant outcomes.

Pregnancy in Patients With Renal Transplant

Risks to mother and fetus can be minimized in patients with kidney transplant when the pregnancy is planned and monitored through a multidisciplinary approach.

Biomarkers Pinpoint Invasive Aspergillosis in Lung Transplant Recipients

Several newly identified biomarkers can help distinguish invasive aspergillosis from aspergillus colonization in lung transplant recipients, according to data from a new study.

Risk of Focal Segmental Glomerulosclerosis Recurrence After Kidney Transplant

With no known cure for focal segmental glomerulosclerosis, many affected patients opt for kidney transplant. But even after kidney transplant, focal segmental glomerulosclerosis can recur.

HIV Infection Not Tied to Cancer Risk After Liver Transplant

Patients with HIV infection who received a liver transplant were not more likely to develop new cancers than recipients without HIV infection over a long-term follow-up. This prospective cohort study assessed involved 1088 patients who underwent liver transplantation between 2002 and 2012.

Donor-Free DNA May Aid Monitoring of Kidney Transplant Recipients

Tests measuring donor-derived cell-free DNA are revolutionizing kidney transplant monitoring, enabling earlier detection of graft injury and decreasing the need for invasive biopsies. Pathologists indicate that dd-cfDNA is a key early indicator of donor-specific antibody development and a superior predictor of transplant rejection compared to serum creatinine.

Can a Common Virus Flag Cancer Risk After Kidney Transplant?

Higher torque teno virus levels after kidney transplant may signal future cancer risk. Researchers analyzed long-term outcomes to test whether viral load reflects excessive immunosuppression. The findings raise questions about how immune monitoring could reshape post-transplant care.

Recipient Plasma Metabolomics as a Predictor of Heart Transplant Severe Primary Graft Dysfunction

Primary graft dysfunction is a significant cause of complications and death after orthotopic heart transplantation, with its underlying biology poorly understood and metabolomics studies being scarce. A study involving 62 OHT recipients analyzed preoperative plasma samples using liquid chromatography–mass spectrometry.

Pediatric Lung Transplants Decline as Case Complexity Intensifies

In the future, there will be fewer operations overall performed on children in need of lung transplants, but more complex cases and mounting challenges will emerge, according to recent data.

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