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Factors Associated with Transplant-Specific Psychological Adaptation Among Heart and Kidney Transplant Recipients

Several psychological factors influence transplant-specific psychological adaptation in heart and kidney transplant recipients. Among heart transplant recipients, improved mental health-related quality of life correlates with better treatment adherence.

Viscoelastic Testing for Hemostatic Assessment in Liver Transplantation

End-stage liver disease leads to a complex coagulation profile characterized by bleeding and clot formation due to reduced coagulation factor production and platelet sequestration. This results in a hypocoagulable state, with elevated factor VIII and von Willebrand factor contributing to thrombosis. Clinicians employ viscoelastic testing to manage this delicate coagulation balance

RSV Tied to Severe Complications in Lung Transplant Patients

Hospitalized adult lung transplant recipients who contract respiratory syncytial virus experience substantial rates of respiratory failure, sustained decreases in graft function and increased mortality, according to multicenter study findings published in Open Forum Infectious Diseases.

Kidney Transplant Stone Treatment Outcomes Rest on Shaky Evidence, Review Finds

Kidney transplant recipients who develop stones in their new organ are usually treated with minimally invasive procedures, yet the evidence behind those treatments is far thinner than the stakes would suggest. A scoping review published in the African Journal of Urology has mapped how outcomes are reported across the literature on so-called graft lithiasis, and it concludes that nearly everything known about success rates rests on pooled, non-comparative figures from small, retrospective series.

Diet Linked to Skin Cancer Prevention After Solid Organ Transplant

Solid organ transplant recipients face an exceptionally high risk of skin cancer, and a review of current evidence suggests that dietary patterns rich in plants and omega-3 fatty acids may help reduce that risk, although transplant-specific trials remain limited and inconsistent.

Letermovir Shows Potential for Preventing Cytomegalovirus in Lung Transplant Recipients With Idiopathic Pulmonary Fibrosis

Among 24 lung transplant recipients with idiopathic pulmonary fibrosis, only one had detectable cytomegalovirus in the blood while taking letermovir for prevention. The drug was well tolerated, including among participants with short telomeres and none developed neutropenia.

Outcomes After Living Donor Liver Transplant for Intrahepatic Cholangiocarcinoma

Intrahepatic cholangiocarcinoma is a severe liver cancer with few curative options. Deceased donor liver transplant may improve survival for some patients with unresectable cases, but outcomes are hindered by high waitlist mortality and the use of expanded criteria grafts due to a shortage of deceased donors.

Kidney Transplant Outcomes Worsen with High Tacrolimus Variability

High tacrolimus intrapatient variability was associated with increased risks of graft loss and rejection following kidney transplantation, according to a systematic review and meta-analysis of 11,647 adult kidney transplant recipients. The findings highlight the potential significance of fluctuations in tacrolimus exposure when assessing long term transplant outcomes, although further evidence is needed before variability can be adopted as a standard clinical monitoring tool.

Nonmuscle-Invasive Bladder Cancer After Solid Organ Transplantation

Solid organ transplant recipients are at a higher risk for bladder cancer and need lifelong immunosuppression, affecting the progression and treatment of nonmuscle-invasive bladder cancer. The challenge lies in balancing cancer control with the preservation of the transplant, and there is a lack of outcome data for this group.

Liver Transplantation for Alcohol-Related Liver Disease in 2026

Liver transplantation for alcohol-related liver disease has shifted from focusing solely on decompensated cirrhosis and prolonged abstinence to also including severe alcohol-related hepatitis and acute-on-chronic liver failure. This change acknowledges the increasing burden of this disease and demonstrates that well-chosen patients with acute conditions can attain high post-transplant survival rates.

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