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Predicting Kidney Transplant Complications Using Infrared Spectroscopy

A Portuguese study suggests a low-cost optical technique could help stratify risk for delayed graft function before transplantation, though researchers caution the findings require larger-scale validation.

A Common Virus May Offer a Safer Way to Tailor Transplant Drugs

Researchers report that using a common, symptom-free virus to guide immunosuppressive dosing after kidney transplant appears safe. The trial hints at more personalized treatment. Experts say the approach could reduce risk without sacrificing organ protection.

Transplant Survival is Improving, But Organ Shortages Persist and Limit Access

While medical and technical advances are helping more people survive the wait for an organ and transplant surgery, organ shortages continue to limit access, a national analysis shows.

Outcomes of DCD Versus DBD Heart Transplantation: Impact of Primary Graft Dysfunction Recovery Trajectory

Donation after circulatory death heart transplantation is associated with higher rates of primary graft dysfunction compared to donation after brain death; however, overall survival rates are similar between the two groups. Recent data suggests equivalent survival outcomes, but the mortality risk linked to primary graft dysfunction in DCD remains unclear.

New CAR T Treatment Opens Doors for Kidney Patients

A pioneering clinical trial has successfully enabled two patients with end-stage kidney disease to receive previously improbable kidney transplants. These individuals were considered among the most difficult in the nation to match with a compatible donor kidney due to harmful antibodies they had developed.

Mold Infections Post Lung Transplant Double All-Cause Mortality Risk

Invasive mold infection-coded diagnoses are common after lung transplantation and are associated with greater acute care use and about a two-fold increased risk of mortality, researchers reported in Chest.

Perfusion Preservation Strategy Boosts Liver Transplant Outcomes

Ischemia-reperfusion injury adds to graft dysfunction after liver transplant, but hypothermic oxygenated perfusion has been shown to improve liver function.

Hyperglycemia Following Pancreas Transplantation

Pancreas transplantation effectively restores euglycemia and insulin independence in patients with diabetes mellitus, but post-transplant diabetes may still develop. This viewpoint presents a practical framework for diagnosing and managing post-transplant diabetes mellitus, highlighting its differentiation from pancreas graft failure and other hyperglycemia causes.

Timing of Palliative Care in Solid Organ Transplantation Reveals Potential Benefits of Early Engagement

Solid organ transplantation extends survival for patients with end-stage disease but involves significant symptom burden and complex decision-making, with palliative care often not consistently integrated into transplant care

Evaluation of Liver Transplantation Outcomes Using Grafts From Brain-Dead Donors With Warfarin-Associated Coagulopathy

Liver transplantation is the primary treatment for end-stage liver disease, especially given the severe organ shortage. This study examines outcomes of liver transplantation using grafts from brain-dead donors who had confirmed warfarin-associated coagulopathy.

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