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Incidence and Outcomes of Candida Bloodstream Infection in Solid Organ Transplant Recipients

Current data indicate limited understanding of Candida bloodstream infection in solid organ transplant recipients due to small sample sizes. Further research is needed to inform targeted prevention strategies and determine the incidence and outcomes of candidemia in this population.

Genetic and Clinical Determinants of Tacrolimus Accumulation in Early Liver Transplantation

Tacrolimus is a primary immunosuppressant used to prevent graft rejection in liver transplantation; however, its narrow therapeutic index and significant pharmacokinetic variability make dosing challenging in the early postoperative period.

Safety and Feasibility of Bilateral Lung Transplantation With Video-Assisted Thoracic Surgery

The clamshell incision is the primary method for bilateral lung transplantation due to its excellent exposure, but it has notable morbidity risks. Video-assisted thoracic surgery presents a less invasive option. This study assesses the feasibility, safety and early postoperative results of the video-assisted thoracic surgery approach.

CT-Derived Body Composition and Diet Quality in Kidney Transplant Recipients

Changes in body composition and diet quality may affect metabolic complications and graft outcomes post-kidney transplantation. This study evaluates the relationship between diet quality, CT-derived body composition components, and their associations with metabolic markers and graft function

Policy Changes Fail to Improve Pediatric Heart Transplant Survival

Researchers have determined that changes to wait-list rules for heart transplants have not enhanced survival rates for infants and children. They conclude that the current prioritization system fails to adequately prioritize the sickest patients, attributing any reduction in mortality to improvements in medical care rather than to changes in wait-list policy.

Ending Race-Based Test Helps Black Kidney Patients

Thousands of Black patients awaiting kidney transplants were advanced on the waiting list after the discontinuation of a specific test. This shift not only benefitted these patients but may also have wider implications for addressing racial inequity in the medical field.

Evaluation Procedure Aims to Make More Donor Lungs Available

To increase the availability of organs, Mayo Clinic Transplant Center is utilizing ex vivo lung perfusion, a procedure that allows surgeons to assess donor lungs for circulation, oxygenation, and compliance with enhanced sensitivity and specificity.

CDC Study Warns on Infection-Related Cancers After Organ Transplant

Cases of suspected Kaposi sarcoma-associated herpesvirus infections in U.S. organ transplant recipients jumped in the last five years, highlighting the need for new screening tools and sharper clinical scrutiny in transplant patients, according to a Centers for Disease Control and Prevention report.

Safety and Efficacy of Liver Transplantation for Hepatocellular Carcinoma With Bile Duct Tumor Thrombus

The prognosis for patients with hepatocellular carcinoma and bile duct tumor thrombus is poor, and there are no established treatment guidelines for this condition. The long-term outcomes of liver transplantation for these patients are uncertain, leaving the appropriateness of this therapy in question.

Kidney Transplant Rates From Brain, Circulatory Death Donors Now Nearly Equal

Three-quarters of kidney transplants in the U.S. come from deceased donors, and donation after circulatory death, in contrast to brain death, now accounts for 45% of all deceased kidney donor transplants, according to study data.

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