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Artificial Intelligence and Predictive Modelling for Precision Dosing of Immunosuppressants in Kidney Transplantation

Optimizing immunosuppressant dosing in kidney transplantation is challenging due to narrow therapeutic ranges and significant inter-patient pharmacokinetic variability.

RSV Vaccination Induces Robust Immune Responses in Solid Organ Transplant Recipients

An observational study published in the American Journal of Transplantation evaluated the cellular and humoral immunogenicity of RSV prefusion F-based vaccines in solid organ transplant recipients and patients with chronic kidney disease.

New Heart Recovery Method May Ease Ethics Concerns With Circulatory Death Donation

A novel way of caring for hearts donated after circulatory death until they can be transplanted showed promise in a case series, with implications for resolving ethical issues around donated after circulatory death procurement.

Leveraging Machine Learning to Predict De Novo Skin Malignancy Following Lung Transplantation

This study focused on predicting posttransplant malignancy risks in lung transplant recipients through machine learning, while also identifying key clinical and immunogenetic predictors.

Public Mistrust Linked to Drop in Deceased Donor Organ Donations and Kidney Transplants

Organ donations from the recently deceased dropped last year for the first time in over a decade, resulting in fewer kidney transplants

Co-Stimulatory Blockade and Infectious Risk in Solid Organ Transplantation

Costimulatory blockade offers a promising alternative to traditional immunosuppression, potentially reducing chronic allograft injury and minimizing drug-related toxicities such as nephrotoxicity, cardiometabolic complications and malignancies.

Expert Guidance On Fecal Microbiota Transplantation in Liver Disease

The gut microbiota is essential for host health and liver function, with fecal microbiota transplantation showing potential as a treatment for chronic liver diseases

New Approaches to Better Regulate the Immune Response After Organ Transplants

The Medical University of Vienna and Therakos, a company specializing in medical technology, have launched a long-term research partnership to further develop extracorporeal photopheresis for solid organ transplantation.

Dual Targeting of B Cell Compartments Using Belatacept and Daratumumab in Highly Sensitized Kidney Transplant Candidates

Highly sensitized kidney transplant candidates encounter challenges in accessing compatible organs because of ongoing anti-HLA antibodies and memory B-cell responses, which are not effectively addressed by existing desensitization therapies.

Incision Techniques in Lung Transplants: A Meta-Analysis

In a groundbreaking study focusing on surgical approaches for bilateral lung transplantation, researchers have conducted a comprehensive meta-analysis to assess the efficacy and outcomes associated with three primary incision techniques: clamshell, median sternotomy and bilateral thoracotomy.

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