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Characteristics and Treatment Outcomes of Portal Hypertension After Living Donor Liver Transplantation

Portal hypertension following liver transplantation is a significant complication that can lead to graft loss, prompting an investigation into its characteristics and treatment outcomes after living donor liver transplantation.

Freeze-Tolerant Frogs Power Organ Cryopreservation Strategies

During winters, some frogs suspend their physiological processes and freeze themselves solid before bouncing back upon thawing in the spring. Scientists are exploring strategies employed by such animals to extend organ cryopreservation durations. Frogs that freeze themselves solid in the winter and thaw in the spring inspired methods to extend the storage time for transplantable organs.

Impact of High Tacrolimus Exposure on Graft Function and Development of a Prediction Model in Kidney Transplant Recipients

To assess the link between early supratherapeutic tacrolimus exposure in kidney transplant recipients and graft outcomes, and to create a prediction model for outcomes associated with this elevated exposure.

Right Ventricular Functional Improvement After Lung Transplantation and Adjunctive Pulmonary Rehabilitation

Right ventricular dysfunction frequently occurs in advanced lung disease caused by chronic pressure overload and changes in pulmonary vascular mechanics. Lung transplantation alleviates RV afterload, and pulmonary rehabilitation can further improve functional recovery.

Outcomes and Risk of Relapse After Living Donor and Deceased Donor Liver Transplantation for Alcohol-Associated Liver Disease

The study examines the six-month abstinence rule for patients with alcohol-associated liver disease regarding liver transplantation. It questions the reliability of this rule in predicting relapse and contrasts the outcomes of deceased donor versus living donor liver transplantation under revised abstinence criteria.

Comparative Outcomes of Transcatheter Arterial Embolization vs Open Surgery for Blunt Abdominal Solid Organ Injury With Concurrent Traumatic Brain Injury

This retrospective observational study analyzed the effectiveness of transcatheter arterial embolization compared to open surgery in patients suffering from blunt abdominal solid organ injuries, specifically to the liver, spleen or kidney, alongside traumatic brain injuries.

Development of Early Diagnostic Strategies by Targeting CXCR3 Following Heart Transplantation

Early diagnosis and treatment of acute rejection are vital for heart transplantation graft survival. This study identifies CXCR3 as a T cell-specific biomarker using single-cell RNA sequencing and develops a nanoparticle-based fluorescent probe targeting CXCR3 for diagnostic evaluation through in vivo imaging.

All About Multiparametric MRI Evaluation in Biliary Tree Complications After Liver Transplant

Multiparametric magnetic resonance imaging plays a crucial role in evaluating biliary tree complications after liver transplantation, integrating into a multidisciplinary team approach for personalized patient treatment.

Pancreas Transplantation in Type 2 Diabetics is Associated with Lower Rates of Graft Rejection and Graft Loss Compared with Type 1 Diabetics

Diabetes mellitus is the leading cause of chronic kidney disease in the United States, and its prevalence is increasing. Type 2 diabetes (T2D) accounts for the vast majority of diabetics (∼95%), while the majority of pancreas transplants are performed in type 1 diabetics (T1D). We sought to compare the outcomes of pancreas transplantation in T1D vs. T2D to validate increased utilization of pancreas transplants in T2D recipients.

Impact of Donor Age on Graft Failure After Deceased Donor Liver Transplantation by Donor-Recipient Sex Combinations: An Analysis of the UNOS OPTN Database

Sex disparities affect many diseases, including liver conditions and transplant outcomes. Female-to-male liver transplantation (LT) is linked to poorer results, not due to surgical mismatch but likely medical factors such as reduced hepatic estrogen signaling. Prior research shows this disadvantage disappears when the donor is over 40 years old. This study investigates whether the same effect occurs in deceased donor LT using UNOS/OPTN data.

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